Additional Oncotype DX Assay-Related Articles

Biologic Determinants of Tumor Recurrence in Stage II Colon Cancer: Validation Study of the 12-Gene Recurrence Score in Cancer and Leukemia Group B (CALGB) 9581
Venook A.P., Niedzwiecki D. Lopatin M., et al.
J Clin Oncol. 2013; 31(14):1775-1781.

Comparison of the prognostic and predictive utilities of the 21-gene Recurrence Score assay and Adjuvant! for women with node-negative, ER-positive breast cancer: results from NSABP B-14 and NSABP B-20
Gong Tang, Steven Shak, Soonmyung Paik, Stewart J. Anderson, Joseph P. Costantino, Charles E. Geyer Jr., Eleftherios P. Mamounas, D. Lawrence Wickerham, Norman Wolmark
Breast Cancer Research Treatment 2010.

Genotypic characterization of phenotypically defined triple-negative breast cancer
J. A. Sparano, L. J. Goldestin, B. H. Childs, S. Shak, S. Badve, F. L. Baehner
Abstract # 500

Molecular characterization of male breast cancer by standardized quantitative RTPCR analysis: First large genomic study of 347 male breast cancers compared to 82,434 female breast cancers.
S. Shak, G. Palmer, F. L. Baehner, C. Millward, D. Watson, G. W. Sledge
Abstract # 549

Biopsy Cavities in Breast Cancer Specimens: Impact on Quantitative RT-PCR Gene Expression Profiles and Recurrence Risk Assessment
FL Baehner, C Quale, C Pomeroy, D Cherbavaz, S Shak.
Abstract # 1574

Development of the 21-Gene Assay and Its Application in Clinical Practice and Clinical Trials
JA Sparano, S Paik

Quantitative gene expression analysis using Oncotype DX in ductal carcinoma in
Baehner FL, Sangli C, Millward C, Cherbavaz D, Goddard A, Shak S Genomic Health,Inc, Redwood City, CA
Abstract # 2066

Analysis of Revised Nottingham Tumor Grade Constitutive Components and Recurrence Free Interval in ECOG Breast Cancer Study E2197
FL Baehner, LJ Goldstein, R Gray, T Maddala, S Shak, GW Sledge, JA Sparano, S Badve
Abstract #82 : Oral Presentation

GRB7-dependent pathways are potential therapeutic targets in triple-negative
Sparano JA, Gray R, Goldstein LJ, Childs BH, Bugarini R, Rowley S, Baker J, Shak S,
Abstract # 25

American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer
L Harris, H Fritsche, R Mennel, L Norton, P Ravdin, S Taube, MR Somerfield, DF Hayes, RC Bast Jr.

Development and Clinical Utility of a 21-Gene Recurrence Score Prognostic Assay in Patients with Early Breast Cancer Treated with Tamoxifen
S Paik

Gene Expression by Standardized Quantitative RT-PCR in the Special Histologic Subtypes of Estrogen Receptor-Positive Invasive Breast Cancer
FL Baehner, D Watson, JT Ballard, G Palmer, S Shak
Abstract #3028 : Poster Session

Association of Individual Genes with Risk of Relapse in Operable Breast Cancer: Analysis of E2197
JA Sparano, L Goldstein, B Childs, C Yoshizawa, S Shak, J Baker, S Rowley, N Davidson, S Badve, GW Sledge Jr., R Gray
Abstract #27

The Impact on the Recurrence Score Due to Patient Variation in the Quantitative Expression of Individual Genes or Gene Groups
D Watson, G Palmer, J Baker, S Shak
Abstract #6039 : Poster Presentation

Relationship Between Proliferation Genes and Expression of Hormone and Growth Factor Receptors: Quantitative RT-PCR in 10,618 Breast Cancers
S Shak, FL Baehner, G Palmer, JT Ballard, J Baker, D Watson
Abstract #6111 : Poster Presentation

Subtypes of Breast Cancer Defined by Standardized Quantitative RT-PCR Analysis of 10,618 Tumors
S Shak, FL Baehner, G Palmer, JT Ballard, J Baker, D Watson
Abstract #6118 : Poster Presentation

Gene Expression Profiles in Formalin-Fixed, Paraffin-Embedded (FFPE) Core Biopsies Predict Docetaxel Chemosensitivity
JC Chang, A Makris, SG Hilsenbeck, JR Hackett, J Jeong, ML Liu, J Baker, K Sexton, CK Osborne, S Shak
Abstract #538 : Poster Discussion

Multiple GSTM Gene Family Members Are Recurrence Risk Markers in Breast Cancer
M Kiefer, K Hoyt, J Hackett, MG Walker, J Baker
Abstract #3604 : Poster Discussion

Adjuvant Chemotherapy for Patients with Estrogen Receptor-Positive Breast Cancer
HJ Burstein, S Paik, P Ravdin, K Albain

Roadmap for Developing and Validating Therapeutically Relevant Genomic Classifiers
R Simon
J Clin Oncol. 2005; 23(29):7332-7341.

Use of Macrodissection in Multi-Gene RNA Analysis of Fixed Paraffin- Embedded Tumor Tissue
R Baehner, B Hiller, CY Kim, C Alexander, ML Liu, M Pho, D Dutta, J Jeong, A Nguyen, M Walker, M Cronin, J Baker, S Paik
Abstract #80

Evaluation of Tumor Gene Expression and K-Ras Mutations in FFPE Tumor Tissue as Predictors of Response to Cetuximab in Metastatic Colorectal Cancer
JB Baker, D Dutta, D Watson, T Maddala, S Shak, EK Rowinsky, L Xu, E Clark, DJ Mauro, S Khambata-Ford
Abstract #3512

Relationship Between Tumor Gene Expression and Recurrence in Patients with Stage II/III Colon Cancer Treated with Surgery + 5-FU/LV in NSABP C-06: Consistency of Results with Two Other Independent Studies
MJ O'Connell, G Yothers, S Paik, IC Lavery, JW Cowens, KM Clark-Langone, MLopatin, JR Hackett, FL Baehner, N Wolmark
Abstract #301 : Poster Session

Relationship Between Tumor Gene Expression and Recurrence in an Observational Cohort of Patients with Stage II/III Colon Cancer Treated with Surgery Only: Quantitative RT-PCR Assay of 375 Genes in Fixed Paraffin-Embedded (FPE) Tissue
I Lavery, J Hammel, J Cowens, K Clark-Langone, J Hackett, F Baehner, G Yothers, M OConnell, N Wolmark
2008; Abstract #302 : Poster Session

Relationship Between Tumor Gene Expression and Recurrence in Stage II/III Colon Cancer: Quantitative RT-PCR Assay of 757 Genes in Fixed Paraffin-Embedded (FPE) Tissue
MJ O’Connell, S Paik, G Yothers, JP Costantino, JW Cowens, KM Clark, J Baker, J Hackett, D Watson, N Wolmark
2006; Abstract #3518 : Poster Discussion

Strategies to Optimize Anti-Receptor Therapies
J Baselga
Poster Session