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Oncotype DX Process As a multi-gene diagnostic assay, Oncotype DX® is designed to support individualized treatment planning. The assay provides a quantitative assessment of the likelihood of distant recurrence, which may increase confidence that the treatment plan is tailored to the individual patient. Oncotype DX is performed in the licensed Genomic Health® laboratory where the assay was developed. First, RNA is extracted from the breast cancer tumor specimen and purified. Next, the RNA is analyzed using a technique called real-time RT-PCR (for a definition of RT-PCR, click here). Finally, the Recurrence Score® is calculated from the gene expression results. An overview of the Oncotype DX process, from sample submission to reporting of results, can be viewed in the animation below. Click here to view an animation of how Oncotype DX works. 
Make a selection below to download the Oncotype DX process animation. For PC users, once the download is complete double-click on the file to uncompress it and double-click on oncotype_demo.exe to run the animation. For Mac users, once the download is complete simply click on the desktop icon. PC Download Mac Download |
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