A provider sits across their desk and talks to an older adult patient.

The Riskguard™ test helps you help your patients

The Riskguard™ test is an assessment tool that can help uncover hereditary cancer risk. The actionable results can help you better understand your patients’ risk level and management options supporting personalized care.

Who can the Riskguard test help?

A three-generation family is happily sitting in a living room discussing the grandmother’s results.

Patients without cancer

The Riskguard test helps inform the risk stratification for patients who have a family history of cancer by identifying variants in clinically actionable cancer-associated genes, from which you can form a customized path.

Customize a prevention path

  • Lifestyle changes
  • Screening programs
  • Risk-reducing medication
  • Risk-reducing surgeries
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Patients with cancer

The Riskguard test can assist with informing an individualized plan for your patients who have been diagnosed with cancer. Knowing about certain gene variants can help you select optimal treatment.1-6

Inform optimal treatment

  • Surgical options
  • Increased surveillance
  • Targeted therapies

More ways to personalize patient care

Add the Riskguard test with our OncoExTra™ genomic profiling test to help increase the number of patients with advanced or metastatic cancer that are eligible for targeted therapies.

Pair the Riskguard test with our Oncotype DX Breast Recurrence Score® test to help inform a more comprehensive treatment plan for newly diagnosed ER+/HER2- breast cancer.

Customize a prevention path

  • Lifestyle changes
  • Screening programs
  • Risk-reducing medication
  • Risk-reducing surgeries

Inform optimal treatment

  • Surgical options
  • Increased surveillance
  • Targeted therapies

More ways to personalize patient care

Add the Riskguard test with our OncoExTra™ genomic profiling test to help increase the number of patients with advanced or metastatic cancer that are eligible for targeted therapies.

Pair the Riskguard test with our Oncotype DX Breast Recurrence Score® test to help inform a more comprehensive treatment plan for newly diagnosed ER+/HER2- breast cancer.

The Riskguard test checks for genes across 10 cancer types

Colorectal, Breast, Prostate, Pancreatic, Ovarian, Endometrial, Skin, Gastric, Kidney, Endocrine
Colorectal, Breast, Prostate, Pancreatic, Ovarian, Endometrial, Skin, Gastric, Kidney, Endocrine

We keep it simple and actionable

We want our results to be simple yet powerful. That’s why we only report on variants in genes you can do something about based on guidelines and published literature. We provide easy-to-understand results that providers and patients can use for personalized care planning. Just the information you need, none of the stuff you don’t.

A minimal illustration of a results report with three highlighted items: summary findings, results, and care points.

Ongoing genetic monitoring and follow-up

You’ll be in the know.

We’ll reach out with updates that impact your patients after the initial results. Once they test, we’ll continue to monitor genetic research for critical changes. As new relevant data becomes available about genes, cancer risk, or medical management, we’ll let you know.*

Proactive updates and outreach

Amended reports for clinically actionable changes

Published data with actionable next steps

New guidelines and screening recommendations

Cutting-edge treatment options

THE GOLD STANDARD OF WHITE-GLOVE SERVICE

Complete access to our premium customer support before, during, and after testing.

On-Demand Customer Care

Call our customer care team for general questions at 1-866-662-6897. You can request the Riskguard test kits and ask about billing, ordering, and how to access results.


Call Customer Care 

GENETIC SUPPORT FOR YOUR PATIENTS

Have your patients ask customer care to connect them with a genetic specialist for more detailed questions. Your patients can learn about the Riskguard test, explore the testing process, and understand possible results and outcomes.

Genetic support for you

Ask customer care to connect you with our genetic counselors for an in-depth consult. We can help you understand and interpret Riskguard test results, including medical management options for your patient.

Billing is easy when you have a support team like ours.

Coverage for eligible patients including Medicare and commercial insurance

Specialized support for billing insurance and prior authorization

Flexible payment options for patients


View Billing and Coverage 

Let’s get started

Clinical testing collection kit box with the Riskguard(TM) Hereditary Cancer Test and Exact Sciences logos on the cover.

REQUEST THE RISKGUARD TEST

Call customer care at 1-866-662-6897 to request our Riskguard test kits, and we’ll send them right to your office. We offer blood and saliva kits so you can select what’s best for your patients.


Call to request the test 

SUBMIT LAB ORDER

Download order form below and fax to 1-715-406-4175. Be sure to also attach order form to blood or saliva specimen and mail with kit to our lab.

OR

Submit an electronic order through our online portal at online.genomichealth.com.


Download order form 
Submit order on our Portal 
The Riskguard(TM) test order form
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ACCESS RESULTS

View patient results on our online portal. For quick and easy access, log in or create an account.


Access results on our portal 

More ways to personalize patient care

Provides individualized genomic insights to help customize treatment for patients with HR+, HER2-early-stage breast cancer.

Offers ultra-comprehensive genomic profiling to aid in therapy selection for patients with advanced disease.

Screens average-risk individuals who are 45 years and older for colon cancer (Rx Only).

FREQUENTLY ASKED QUESTIONS


WE’RE HERE FOR YOU

With questions about ordering the Riskguard test, insurance billing and payment options, checking results, or getting connected with a genetic counselor, call us at 1-866-662-6897 or email us at riskguard@exactsciences.com.


*The terms of this product offering are subject to change and not offered permanently or in perpetuity. Any modifications are to be considered effective once published on this website

Risguard test kits are provided at no charge and are to be used only with the Riskguard test.

Data on file


The Exact Sciences Riskguard test was developed, and its performance characteristics validated by an Exact Sciences laboratory following College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA) regulations. The test is performed in Marshfield, WI at PreventionGenetics LLC, a wholly owned subsidiary of Exact Sciences. PreventionGenetics is accredited by CAP, certified under CLIA regulations, and qualified to perform high-complexity clinical laboratory testing. It has not been cleared or approved by the US Food and Drug Administration or other notified regulatory authority.